Short-term effects associated with heroin use include a warm flushing of the skin, dry mouth, and heavy extremities.
Ketamine is abused recreationally massive numbers of young people as a "club drug," and is often distributed at "raves", which are popular all night dance parties.
The more you consume alcohol every day, the more likely you are to develop alcohol withdrawal symptoms when you stop drinking.
Opiates act directly on the respiratory center in the brainstem, causing a slow in activity resulting in a decrease in breathing rate.