Physical dependence to amphetamine occurs when the body has adapted to the presence of these drugs, and withdrawal symptoms occur if its use is stopped abruptly.
Just one hit of Ecstasy causes effects which can last for 3 to 6 hours.
Repeated, heavy use of crack cocaine will eventually lead to decreased sexual desire, which may lead to total abstinence from sex. Impotence in males is also possible.
The severity and duration of Vicodin withdrawal symptoms can vary, depending on the dosage and length of time the individual has been using the drug.