Opana dulls an individual's perception of pain, and at higher doses it can affect other systems such as those that control respiration and circulation.
LSD can induce delusions and visual hallucinations which may distort the user's sense of time and identity.
The rate of high school students in the U.S. reporting PCP use at least once fell from 13% in 1979 to less than 3% in 1990.
Physical drug withdrawal may cause changes in heart rate and blood pressure.