PCP users may experience feelings of invulnerability and exaggerated strength, and some users may become severely disoriented, violent, or suicidal.
Opiate users who inject their drug of choice are at risk from infections from unsterile solutions, syringes, and needles which can cause illnesses such as liver disease, tetanus, and serum hepatitis.
Persons with HIV who consume alcohol and fail to take their medications or do not take them correctly, it increases the likelihood that the virus will become resistant to any form of therapy.
There is an increase in the risk of rape or sexual assault when both the attacker and victim have been drinking heavily prior to the attack.