Methadone, along with single-ingredient and combination forms of oxycodone and hydrocodone, was one of the most frequently reported drugs in terms of nonmedical use in emergency room visits in 2009.
Marijuana withdrawal can sometimes make individuals feel like they have a low-grade flu.
Methamphetamine may dry mucosa which may then lead to more chafing and abrasions in the genital area, which could make methamphetamine users more susceptible to HIV during sexual activity.
Typical symptoms of opiate or synthetic opioid withdrawal include restlessness, muscle and bone pain, insomnia, diarrhea, vomiting, cold flashes with goose bumps ("cold turkey"), and leg movements.