Physical dependence and withdrawal symptoms are known to develop after only five days of the administration of Morphine.
Opiate users who inject their drug of choice are at risk from infections from unsterile solutions, syringes, and needles which can cause illnesses such as liver disease, tetanus, and serum hepatitis.
Studies indicate that 31% of students met criteria for a diagnosis of alcohol abuse and 6% for alcohol dependence in the past 12 months.
One person may have a "bad trip" on a low dose of LSD, while someone else who uses the drug often can take a high dose and get through it without distress.