LSD acquired at street level is very often impure and can contain various other chemicals, such as "PCP" or "speed".
One option that is sometimes used to avoid opiate withdrawal is to replace the individual's drug of choice with methadone, a long-acting, cross-tolerant opiate that does not normally produce a "high."
Street heroin may contain additives that won't dissolve, which can result in clogged blood vessels which lead to the lungs, liver, kidneys, or brain. This can cause infection or even death of small patches of cells in vital organs.
Rates of anabolic steroid use are highest among males, but rates among females are growing most rapidly.