Things which may influence a LSD trip are their "mindset", the user's expectations, experience and mood at the time the drug is taken as well as the setting or place where they are using LSD.
Opana is often administered in clinical settings to treat individuals who are experiencing moderate to severe pain for an extended period of time
Research has shown that psychosocial factors, antisocial personality disorder and alcohol dependence can play a role in long-term marijuana use.
Research indicates that there is a link between nitrate abuse and the development and progression of infectious diseases and tumors.