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 Chronic use of opioids can result in tolerance, which means that users must take higher doses to achieve the same effects. Long-term use also can lead to physical dependence and addiction; withdrawal can occur when an individual discontinues use of the dr
Withdrawal symptoms from heroin begin within 24 hours after last use and may last up to 7-10 days.
Taken orally once a day, methadone suppresses narcotic withdrawal for between 24 and 36 hours.
Alcoholics continue to work and socialize reasonably well, their deteriorating physical condition may go unrecognized by others until severe damage develops - or until they are hospitalized for other reasons and suddenly experience alcohol withdrawal symp | 

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The tragedy of the drug babies withdrawal
THE number of babies born addicted to drugs in Greater Manchester has soared to an all-time high.
During the past year, more than 300 children came into the world in local hospitals affected by their mothers' habits.
Many of the newborn babies have to go through the trauma of withdrawal. Some even have to be given morphine in a last-ditch attempt to cure their addiction.
All hospitals in Greater Manchester are now geared up to treating pregnant addicts - women from all social classes hooked on heroin, crack cocaine, tranquillisers and the heroin substitute methadone - as their numbers continue to rise.
Many hospitals have found the figures have doubled or even trebled over the last 10 years.
The figures will shock many, but medics have welcomed the trend as evidence that more women are asking for help.
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