The acetaminophen component in Vicodin can on its own put the user at risk of overdose.
Tolerance to methadone when administered in a pain-control program usually occurs during the first few weeks.
Someone's blood alcohol concentration can continue to rise even while he or she is unconscious.
Over 30 percent (658,263) of all drug abuse emergency room visits in 2009 involved the use of alcohol, either alone or in combination with another drug.