Things which may influence a LSD trip are their "mindset", the user's expectations, experience and mood at the time the drug is taken as well as the setting or place where they are using LSD.
Opiate addicted individuals who do not receive regular doses of opiates begin going through withdrawal, which is a very painful process.
One study in a state prison found that prisoners who participated in a drug rehab program and continued to receive treatment in a work-release program after prison were 70 percent less likely than nonparticipants to return to drug use and be re-arrested.
Prescription central nervous system depressants slow down brain function, and if combined with other medications that cause drowsiness or with alcohol, heart rate and respiration can slow down dangerously.