With repeated use, crack cocaine users typically develop a tolerance to the drug.
The signs and symptoms of a Lortab overdose are similar to that of a heroin overdose, and the individual will become extremely sleepy and may struggle to stay conscious.
Proponents of methadone maintenance often state that patients receiving treatment are "dependent" on the medication, not "addicted".
There have been numerous reports of heroin users switching to Opana because they can achieve an even more intense high on this prescription opioid than they could on heroin.