Most deaths as a result of inhalant abuse are due to repetitive inhalation, which can lead to extremely high concentrations of inhaled fumes, which displaces the available oxygen in the lungs.
Inhaling benzene to get high, an additive found in gasoline, can cause severe injury to bone marrow, and increase the risk of leukemia.
Opiate injection caused the users to experience a more effective and timely high, which produces an intense feeling of pleasure followed by a sense of well-being and a calm drowsiness.
Methamphetamine is used recreationally and illicitly among college students, truck drivers and athletes in the U.S. for the increased energy and alertness that the drug produces.