Methamphetamine withdrawal symptoms that individuals commonly experience when they stop using the drug suddenly are fatigue, depression anxiety, irritability, headaches, agitation, an inability to remain still, excessive sleeping, vivid or lucid dreams, deep REM sleep and suicidal ideation and an increased appetite.
When someone injects heroin intravenously this is called mainlining.
When an individual is experiencing the withdrawal symptoms due to a lack of heroin or other opiates, this is commonly referred to as going "cold turkey".
Irreversible effects caused by inhalant abuse can include hearing loss, limb spasms, central nervous system or brain damage, or bone marrow damage.