Symptoms of marijuana withdrawal first appear in chronic users within 24 hours. They are most pronounced for the first 10 days and can last up to 28 days.
Side effects associated with use of OxyContin are constipation, nausea, sedation, dizziness, vomiting, headache, dry mouth, sweating, mood changes, flushing, loss of appetite, and weakness.
Once the cocaine high dissipates, the user can expect to experience agitation, depression, anxiety, paranoia and decreased appetite.
Studies indicate that as much as half of the dopamine-producing cells in the brain can be damaged by prolonged exposure to relatively low levels of methamphetamine.