Opiate use and addiction is directly associated with at least 50% of the major crimes in the U.S.
When Ecstasy was first synthesized it was thought that it may be of use as an appetite suppressant.
Failure to recognize antidepressant withdrawal may result in medical and psychiatric misdiagnosis, potentially causing individuals to undergo unnecessary diagnostic investigations or potentially risky medical interventions.
The U.S. first took action to control the distribution and use of heroin through the Harrison Narcotic Act of 1914.