The Tarnak Farm incident during WW II, in which an American F-16 pilot killed several friendly Canadian soldiers on the ground, resulted from the pilot's use of amphetamine.
Inhaling nitrates may sometimes enhance sexual pleasure and performance.
Magic mushrooms are sometimes made more appetizing by washing them down with water or orange juice, or making into a tea with ginger and honey.
One of the reasons it is so hard to stop taking Vicodin is because of the intense withdrawal symptoms that occur as a result of abrupt cessation of use.