Only heroin, which is almost identical in terms of chemical structure to morphine, can be closely compared when considering dependence liability.
Because central nervous system depressants work by slowing the brain's activity, when an individual stops taking the drug this activity can rebound and as part of withdrawal seizures can occur.
Inhaling nitrates may sometimes enhance sexual pleasure and performance.
The psychological effects of drug withdrawal can include extreme anxiety, nervousness, rapid mood changes and irritability.