Studies show that alcohol consumption may interfere directly with medications used for HIV, essentially blocking their effectiveness.
An individual who is considering ending use of central nervous system depressants, or who has stopped and is suffering withdrawal should seek medical treatment due to the dangers involved in withdrawal from CNS depressants.
PCP's effects are often unpredictable and some users report feeling the drug's effects for days.
Methadone, along with single-ingredient and combination forms of oxycodone and hydrocodone, was one of the most frequently reported drugs in terms of nonmedical use in emergency room visits in 2009.